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Oxycontin is a strong opioid, which means that it is the type of drug that changes how your brain and nervous system respond to pain.For opioid-naive patients, the usual starting dose is 10 mg every 12 hours, although many patients require higher doses of 30 mg. The dosage must be titrated to the individual patient's previous opioid use, pain severity, and clinical response. They should not exceed the prescribed dose. Let your physician know if you have a history of substance abuse, respiratory disorders, liver or kidney diseases, or if you are pregnant or a breastfeeding mom.